tract infection
Clinician-in-the-Loop Smart Home System to Detect Urinary Tract Infection Flare-Ups via Uncertainty-Aware Decision Support
Ugwu, Chibuike E., Fritz, Roschelle, Cook, Diane J., Doppa, Janardhan Rao
Urinary tract infection (UTI) flare-ups pose a significant health risk for older adults with chronic conditions. These infections often go unnoticed until they become severe, making early detection through innovative smart home technologies crucial. Traditional machine learning (ML) approaches relying on simple binary classification for UTI detection offer limited utility to nurses and practitioners as they lack insight into prediction uncertainty, hindering informed clinical decision-making. This paper presents a clinician-in-the-loop (CIL) smart home system that leverages ambient sensor data to extract meaningful behavioral markers, train robust predictive ML models, and calibrate them to enable uncertainty-aware decision support. The system incorporates a statistically valid uncertainty quantification method called Conformal-Calibrated Interval (CCI), which quantifies uncertainty and abstains from making predictions ("I don't know") when the ML model's confidence is low. Evaluated on real-world data from eight smart homes, our method outperforms baseline methods in recall and other classification metrics while maintaining the lowest abstention proportion and interval width. A survey of 42 nurses confirms that our system's outputs are valuable for guiding clinical decision-making, underscoring their practical utility in improving informed decisions and effectively managing UTIs and other condition flare-ups in older adults.
Adverse Event Extraction from Discharge Summaries: A New Dataset, Annotation Scheme, and Initial Findings
Guellil, Imane, Andres, Salomรฉ, Anand, Atul, Guthrie, Bruce, Zhang, Huayu, Hasan, Abul, Wu, Honghan, Alex, Beatrice
In this work, we present a manually annotated corpus for Adverse Event (AE) extraction from discharge summaries of elderly patients, a population often underrepresented in clinical NLP resources. The dataset includes 14 clinically significant AEs-such as falls, delirium, and intracranial haemorrhage, along with contextual attributes like negation, diagnosis type, and in-hospital occurrence. Uniquely, the annotation schema supports both discontinuous and overlapping entities, addressing challenges rarely tackled in prior work. We evaluate multiple models using FlairNLP across three annotation granularities: fine-grained, coarse-grained, and coarse-grained with negation. While transformer-based models (e.g., BERT-cased) achieve strong performance on document-level coarse-grained extraction (F1 = 0.943), performance drops notably for fine-grained entity-level tasks (e.g., F1 = 0.675), particularly for rare events and complex attributes. These results demonstrate that despite high-level scores, significant challenges remain in detecting underrepresented AEs and capturing nuanced clinical language. Developed within a Trusted Research Environment (TRE), the dataset is available upon request via DataLoch and serves as a robust benchmark for evaluating AE extraction methods and supporting future cross-dataset generalisation.
Urinary Tract Infection Detection in Digital Remote Monitoring: Strategies for Managing Participant-Specific Prediction Complexity
Fan, Kexin, Capstick, Alexander, Nilforooshan, Ramin, Barnaghi, Payam
Urinary tract infections (UTIs) are a significant health concern, particularly for people living with dementia (PLWD), as they can lead to severe complications if not detected and treated early. This study builds on previous work that utilised machine learning (ML) to detect UTIs in PLWD by analysing in-home activity and physiological data collected through low-cost, passive sensors. The current research focuses on improving the performance of previous models, particularly by refining the Multilayer Perceptron (MLP), to better handle variations in home environments and improve sex fairness in predictions by making use of concepts from multitask learning. This study implemented three primary model designs: feature clustering, loss-dependent clustering, and participant ID embedding which were compared against a baseline MLP model. The results demonstrated that the loss-dependent MLP achieved the most significant improvements, increasing validation precision from 48.92% to 72.60% and sensitivity from 27.44% to 70.52%, while also enhancing model fairness across sexes. These findings suggest that the refined models offer a more reliable and equitable approach to early UTI detection in PLWD, addressing participant-specific data variations and enabling clinicians to detect and screen for UTI risks more effectively, thereby facilitating earlier and more accurate treatment decisions.
Experts Weigh In On The Great Hopes For Artificial Intelligence In Medicine And The Ethical Pitfalls That Come With It
Artificial intelligence has the potential to better patient care while creating cost-efficiencies that would be impossible without it. But it could also worsen racial disparities, have profit outweighing patient care, or simply lead to mistakes that a human wouldn't make. In other news at the intersection of health care and technology: video games, virtual reality for nursing home patients and ways to identify bacteria's genetic makeup. Artificial intelligence can make diagnoses from digitized images such as mammograms and diabetic retinal scans. More sophisticated interventions might also be possible someday: algorithms that guide robots through surgery, for example, or even help restore motor control in paralyzed patients.